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Heart Disease reviews by topic

Issue 7, 2010 of The Cochrane Library included 2 reviews and 1 protocol on the treatment and prevention of heart disease.  A full list of topics and reviews can be viewed below. 

Click on the title to view the full review or protocol

Log on to The Cochrane Library to read protocols and full reviews. (click here for search tip)

[R] Cochrane review

[P] Protocol for Cochrane review
[S] Summary of Cochrane review available

Quick links to heart disease topics on this page:

Topics and reviews on other cardiovascular disease areas can be viewed on this site:

Topic Reviews and Protocols 
Click on title to view review or protocol
Myocardial ischaemia/coronary disease - Drug interventions Andrenergic agents
  1. No reviews currently available for this topic
Antibiotics
  1. Antibiotics for secondary prevention of coronary heart disease  [P]
Thrombolytics / Fibrinolytics (Antiplatelets /Anticoagulants / Clopidgrel / Ticlopidine)
  1. Clopidogrel and aspirin versus aspirin for preventing cardiovascular disease in those at high risk  [R]
  2. Oral anticoagulants for the secondary prevention of coronary heart disease  [P]
  3. Ticlopidine versus oral anticoagulation for coronary stenting  [R]
Lipid lowering drugs
  1. Combined therapy with statins and fibrates for people with dyslipidaemia  [P]

Other Interventions

  1. Amiodarone versus other pharmacological interventions for prevention of sudden cardiac death  [P]
  2. Chelation therapy for atherosclerotic cardiovascular disease   [R]  [S]
  3. Effect of early treatment with anti-hypertensive drugs on short and long-term mortality in patients with an acute cardiovascular event  [R]
  4. Stem cell therapy for ischaemic heart disease and congestive heart failure  [P]

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Myocardial ischaemia/coronary disease - Lifestyle interventions Diet
  1. Low glycaemic index diets for coronary heart disease  [R]
  2. Ganoderma lucidum for the treatment of cardiovascular risk factors  [P]
  3. Wholegrain cereals for coronary heart disease  [R]
Exercise/Rehabilitation
  1. Bed rest for acute uncomplicated myocardial infarction  [R]
  2. Exercise-based rehabilitation for coronary heart disease  [R]  [s]
  3. Promoting patient uptake and adherence in cardiac rehabilitation  [P]
Smoking cessation
  1. Psychosocial interventions for smoking cessation in patients with coronary heart disease [R]
  2. Smoking cessation for the secondary prevention of coronary heart disease  [R] [s]

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Myocardial ischaemia/coronary disease - Psychological  interventions Counselling/education
  1. No reviews currently available for this topic
Other
  1. Psychological interventions for coronary heart disease  [R]  [s]

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Myocardial ischaemia/coronary disease - Surgical  interventions Coronary Artery Bypass Grafting (CABG)
  1. Bilateral versus single internal mammary artery bypass grafts for coronary arterial atherosclerosis  [P]
  2. Carotid endarterectomy for carotid stenosis in patients selected for coronary artery bypass graft surgery  [R]
  3. Hypothermia to reduce neurological damage following coronary artery bypass surgery  [R]
  4. Incentive spirometry for preventing pulmonary complications after coronary artery bypass graft  [R]
  5. Local versus general anaesthesia for carotid endarterectomy  [R]  [S]
  6. Off-pump versus conventional coronary artery bypass grafting for coronary artery disease  [P]
  7. Off-pump versus on-pump coronary artery bypass grafting for ischaemic heart disease  [P]
  8. Patch angioplasty versus primary closure for carotid endarterectomy  [R]  [S]
  9. Patches of different types for carotid patch angioplasty  [R]  [S]
  10. Preoperative intra aortic balloon pumps in high risk patients undergoing coronary artery bypass grafting  [R]
  11. Prophylactic corticosteroids for cardiopulmonary bypass in adults  [P]
  12. Prophylactic corticosteroids for pediatric open heart surgery  [P]
  13. Staples versus sutures for closing leg wounds after vein graft harvesting for coronary artery bypass surgery  [R]
Percutaneous Transluminal Coronary Angiography (PTCA)
  1. No reviews currently available for this topic

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Myocardial ischaemia/coronary disease - Complementary therapies  
  1. No reviews currently available for this topic

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Myocardial ischaemia/coronary disease - Other (including organisational)
  1. Home-based versus centre-based cardiac rehabilitation  [P]
  2. Service organisation for the secondary prevention of ischaemic heart disease  [P]

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Angina - Drug interventions Andrenergic agents / Calcium channel blockers / Lipid lowering agents / Nitrates / Thrombolytics / Fibrinolytics 
  1. Beta blockers for stable angina  [P]
  2. Nitrates for stable angina  [P]
Vasodilators
  1. Trimetazidine for stable angina  [R]  [S]

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Angina - Surgical interventions
  1. Transmyocardial laser revascularization versus medical therapy for refractory angina  [R]

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Angina - Complementary therapies
  1. Compound red sage root dropping pill versus nitrate for angina pectoris  [P]
  2. Suxiao jiuxin wan for angina pectoris  [P]
  3. Traditional Chinese herbal products for stable angina  [R]

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Acute coronary syndrome (myocardial infarction/unstable angina) - Drug interventions Andrenergic agents 
  1. Beta-blockers for myocardial infarction  [P]
  2. Beta-blockers for unstable angina  [P]
Lipid lowering agents
  1. Statins for acute coronary syndrome  [P]
Thrombolytics/Fibrinolytics - Antiplatelets
  1. Platelet glycoprotein IIb/IIIa blockers for percutaneous coronary revascularization, and unstable angina and non-ST-segment elevation myocardial infarction  [R]
Thrombolytics/Fibrinolytics - Anticoagulants
  1. Heparin for ST-segment elevation myocardial infarction  [P]
  2. Heparin versus placebo for acute coronary syndromes  [R]
  3. Low molecular weight heparins versus unfractionated heparin for acute coronary syndromes  [R] [s]
  4. Xa inhibitors for acute coronary syndromes  [P]

Other

  1. Intravenous magnesium for acute myocardial infarction  [R]
  2. Prophylactic lidocaine for myocardial infarction  [P]
Antiarrhythmics / Calcium channel blockers / Nitrates / Clopidigrel / Ticlopidine / Vasodilators
  1. Calcium antagonists for unstable angina  [P]

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Acute coronary syndrome (myocardial infarction/unstable angina) - Surgical interventions Coronary Artery Bypass Grafting (CABG)
  1. No reviews currently available for this topic
Percutaneous Transluminal Coronary Angiography (PTCA)
  1. Percutaneous transluminal angioplasty and stenting for carotid artery stenosis  [R]  [S]
  2. Percutaneous transluminal coronary angioplasty with stents versus coronary artery bypass grafting for people with stable angina or acute coronary syndromes  [R]  [S]
Stents
  1. Drug-eluting stents versus bare metal stents for angina or acute coronary syndromes  [R]
Other
  1. Intra-aortic balloon pump counterpulsation (IABP) for myocardial infarction complicated by cardiogenic shock  [P]
  2. Percutaneous transluminal rotational atherectomy for coronary artery disease  [R]  [s]

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Acute coronary syndrome (myocardial infarction/unstable angina) - Complementary treatments
  1. Chinese medicinal herbs "Dan Shen" compound for acute myocardial infarction  [P]
  2. Danshen (Chinese medicinal herb) preparations for acute myocardial infarction  [R]
  3. Puerarin for unstable angina  [R]  [S]
  4. Tongxinluo capsule for unstable angina pectoris  [R]  [S]

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Acute coronary syndrome (myocardial infarction/unstable angina) - Others 
  1. Bed rest for acute myocardial infarction  [R]
  2. Chest pain observation units for patients with symptoms suggestive of acute cardiac ischaemia  [P]
  3. Hyperbaric oxygen therapy for acute coronary syndrome  [R]  [S]
  4. Oxygen therapy for acute myocardial infarction  [R]
  5. Stem cell treatment for acute myocardial infarction  [R]

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Heart arrest - Drugs
  1. Adrenaline and vasopressin for cardiac arrest  [P]
  2. Aminophylline for bradyasystolic cardiac arrest in adults  [P]
  3. Biphasic versus monophasic waveforms for transthoracic defibrillation in out-of-hospital cardiac arrest  [P]

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Heart arrest - Non drugs
  1. Active chest compression-decompression for cardiopulmonary resuscitation  [R]
  2. Hypothermia for neuroprotection in adults after cardiopulmonary resuscitation  [R]

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Heart arrest - Organisational Prehospital interventions (coronary ambulances) / General public cardiopulmonary resuscitation training
  1. No reviews currently available for this topic

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Abnormal heart rhythms - atrial fibrillation - Drugs All drugs 
  1. Pharmacological cardioversion for atrial fibrillation/flutter  [R]  [S]
Cardiac glycosides
  1. Digoxin for cardioversion in patients with atrial fibrillation  [P]
Thrombolytics/Fibrinolytics - Antiplatelets
  1. No reviews currently available for this topic
Thrombolytics/Fibrinolytics - Anticoagulants
  1. Self management for oral anticoagulation  [P]
  2. Self-monitoring and self-management of oral anticoagulation  [R]
Thrombolytics/Fibrinolytics - Clopidigrel/Ticlopidine
  1. No reviews currently available for this topic
ACE inhibitors / Andrenergic agents / Antiarrhythmics / Calcium channel blockers / Diuretics / Lipid lowering agents / Nitrates / Phosphodiesterase inhibitors / Potassium channel blockers / Vasodilators
  1. Antiarrhythmics for maintaining sinus rhythm after cardioversion of atrial fibrillation  [P]

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Abnormal heart rhythms - atrial fibrillation - Electrical pacing
  1. Dual versus single chamber ventricular pacemakers in sick sinus syndrome and atrioventricular block  [R]  [S]
  2. Electrical cardioversion for atrial fibrillation and flutter  [R]  [S]

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Abnormal heart rhythms - Other types
  1. Catheter ablation for paroxysmal and persistent atrial fibrillation  [P]

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Heart failure and left ventricular dysfunction - Drugs Angiotensin converting enzyme (ACE) inhibitors 
  1. Angiotensin converting enzyme inhibitors for heart failure  [P]
Angiotensin II antagonists 
  1. Angiotensin receptor blockers for heart failure  [P]
Adrenergic agents
  1. Beta blockers for congestive heart failure in children  [P]
  2. Beta-blockers for heart failure  [P]
Calcium channel blockers
  1. Second generation dihydropyridine calcium channel blockers for heart failure  [P]

Cardiac glycosides

  1. Digitalis for treatment of congestive heart failure in patients in sinus rhythm  [R]  [s]
Diuretics
  1. Continuous infusion versus bolus injection of loop diuretics in congestive heart failure  [R]  [S]
  2. Diuretics for heart failure  [R]
  3. Nitrates for acute heart failure  [P]

Phosphodiesterase inhibitors

  1. Phosphodiesterase III inhibitors for heart failure  [R]  [S]

Thrombolytics/Fibrinolytics - Antiplatelets

  1. Antiplatelet agents versus control or anticoagulation for heart failure in sinus rhythm  [R]
Thrombolytics/Fibrinolytics - Anticoagulants
  1. Anticoagulation for heart failure in sinus rhythm  [R]
Thrombolytics/Fibrinolytics - Clopidigrel/Ticlopidine
  1. No reviews currently available for this topic
Antiarrhythmics / Antiobiotics / Anti-inflammatory agents / Nitrates / Potassium channel blockers / Vasodilators
  1. No reviews currently available for this topic

Other

  1. Hawthorn extract for treating chronic heart failure [R]

 

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Heart failure and left ventricular dysfunction  - Surgical interventions
  1. No reviews currently available for this topic

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Heart failure and left ventricular dysfunction  - Electrical/Pacing
  1. Dual chamber versus single chamber ventricular pacemakers for sick sinus syndrome and atrioventricular block  [R]  [S]
  2. Implantable defibrillators vs antiarrhythmic drugs for left ventricular dysfunction  [P]

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Heart failure and left ventricular dysfunction   - Lifestyle
  1. Exercise based rehabilitation for heart failure  [R]

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Heart failure and left ventricular dysfunction   - Psychological
  1. Psychological interventions for depression in heart failure  [R]  [S]

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Heart failure and left ventricular dysfunction   - Complementary treatments
  1. Shengmai (traditional Chinese herbal medicine) for heart failure  [R]

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Heart failure and left ventricular dysfunction   - Organisational
  1. Clinical service organisation for heart failure  [R]  [S]

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Myocardial disease  - Chagas cardiomyopathy Drugs
  1. Trypanocidal drugs for chronic asymptomatic Trypanosoma cruzi infection  [R]
  2. Trypanocidal drugs for late stage, symptomatic Trypanosoma cruzi infection (Chagas disease)  [R]
Surgery
  1. No reviews currently available for this topic

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Myocardial disease  - dilated cardiomyopathy
  1. No reviews currently available for this topic

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Myocardial disease  - hypertrophic cardiomyopathy
  1. Pacing for drug-refractory or drug-intolerant hypertrophic cardiomyopathy  [P]

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Myocarditis
  1. Corticosteroids for viral myocarditis  [R]
  2. Herbal medicines for viral myocarditis  [R]

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 Endocarditis
  1. No reviews currently available for this topic

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Rheumatic heart disease Drugs
  1. Anti-inflammatory treatment for carditis in acute rheumatic fever  [R]  [s]
  2. Penicillin for secondary prevention of rheumatic fever  [R]

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Heart valve disease - Drugs Antibiotic prophylaxis
  1. No reviews currently available for this topic
Adrenergic agents
  1. Beta-blockers for mitral stenosis  [P]
Cardiac glycosides
  1. No reviews currently available for this topic
Thrombolytics / Fibrinolytics
  1. Antiplatelet and anticoagulation for patients with prosthetic heart valves  [R] [s]

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Heart valve disease - Surgery Balloon valvuloplasty
  1. No reviews currently available for this topic
Valve repair
  1. No reviews currently available for this topic
Valve replacement
  1. Antiplatelet and anticoagulation for patients with prosthetic heart valves  [R]  [S]

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Heart surgery (not specific to disease areas)
  1. Antibiotics and antiseptics to prevent infection in cardiac rhythm management device implantation surgery  [P]
  2. Beta-adrenergic blockers for perioperative cardiac risk reduction in patients undergoing vascular surgery  [P]
  3. Early extubation for adult cardiac surgical patients  [R]  [s]
  4. Fresh frozen plasma for cardiovascular surgery  [P]
  5. Interventions for preventing post-operative atrial fibrillation in patients undergoing heart surgery  [R]  [S]
  6. Interventions for treating tuberculosis pericarditis  [R]  [S]
  7. Mediastinal chest drain clearance for cardiac surgery  [R]  [S]

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Other
  1. Cognitive behavourial therapy for patients with implantable cardioverter-defibrillators  [P]
  2. Drugs and pacemakers for neurally mediated reflex syncope  [P]
  3. Erythropoiesis-stimulating agents for anaemia in chronic heart failure patients  [R]
  4. Preoperative statin therapy for patients undergoing cardiac surgery  [P]
  5. Psychological interventions for symptomatic management of non-specific chest pain in patients with normal coronary anatomy  [R]
  6. Treatment of valvular heart disease during pregnancy for improving maternal and neonatal outcome  [P]

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Last updated 19 Jul 2010

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