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Arthritis and Musculoskeletal reviews by topic

Issue 2, 2008 of The Cochrane Library included 4 reviews and 3 protocols on arthritis and musculoskeletal disease.   A full list of topics and reviews can be viewed below. 

Click on the title to view the full review or protocol

Log on to The Cochrane Library to read protocols and full reviews. (click here for search tip)

[R] Cochrane review

[P] Protocol for Cochrane review

[S] Summary of Cochrane review available

Quick links to topics:

Topic Reviews and Protocols 
Click on title to view review or protocol
Osteoarthritis - Prevention
  1. No reviews on this topic

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Osteoarthritis - Pharmacological Treatment Analgesia
  1. Opioid therapy for treating osteoarthritis pain  [P]
  2. Chloroquines for the treatment of osteoarthritis  [P]
  3. Tramadol for osteoarthritis  [R]  [S]

Chondroitin

  1. Chondroitin for osteoarthritis  [P]
Glucosamine
  1. Glucosamine therapy for treating osteoarthritis  [R]
Intra-articular injections
  1. Intraarticular corticosteroids for osteoarthritis of the knee  [R]  [S]
Non-steroidal anti-inflammatory drugs (NSAID)
  1. Acetaminophen for osteoarthritis  [R]  [S]
Selective Cox 2 inhibitors
  1. Rofecoxib for osteoarthritis  [R]
Viscosupplemenation
  1. Viscosupplementation for osteoarthritis of the knee  [R]
Hormone replacement therapy
  1. Hormone replacement therapy for osteoarthritis in peri-menopausal and post-menopausal women  [P]

Biologics

  1. Diacerein for osteoarthritis  [R]  [S]

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Osteoarthritis - Non-Pharmacological Treatment Alternative therapies (eg. acupuncture)
  1. Acupuncture for osteoarthritis  [P]
  2. Herbal therapy for treating osteoarthritis  [R]
  3. Homeopathy for osteoarthritis  [P]
Balneotherapy
  1. Balneotherapy for rheumatoid arthritis  [R]
  2. Balneotherapy for osteoarthritis  [R]
Laser therapy
  1. Low level laser therapy (Classes I, II and III) for treating osteoarthritis  [R]  [S]
Surgery
  1. Mobile bearing and fixed bearing prostheses for total knee arthroplasty for post-operative functional status in patients with osteoarthritis and rheumatoid arthritis  [R]  [S]
  2. Posterior versus lateral surgical approach for total hip arthroplasty in adults with osteoarthritis  [R]  [S]
  3. Osteotomy for treating knee osteoarthritis  [R]  [S]
  4. Surgery for thumb (trapeziometacarpal joint) osteoarthritis  [R]
  5. Metal versus non-metal backing of the tibial component for total knee replacement for osteoarthritis and/or rheumatoid arthritis  [P]
  6. Retention versus sacrifice of the posterior cruciate ligament in total knee replacement for treatment of osteoarthritis and rheumatoid arthritis  [R]
  7. Minimally invasive surgical approaches for total hip athroplasty in adults with osteoarthritis  [P]
  8. Patella resurfacing in total knee arthroplasty  [P]
  9. Arthroscopic debridement for knee osteoarthritis  [R]
  10. Non-steroidal anti-inflammatory drugs for preventing heterotophic bone formation after hip arthroplasty  [R]  [S]
  11. Computer assisted knee arthroplasty for osteoarthritis and other non-traumatic diseases  [P]
  12. Surgical approaches in total knee arthroplasty  [P]
  13. Cemented versus cementless surgical approach for total hip arthroplasty revision  [P]
  14. Operative and non‑operative treatment options for dislocation of the hip following total hip arthroplasty  [R]
  15. Processed versus fresh frozen bone for impaction bone grafting in revision hip arthroplasty  [P]
TENS
  1. Transcutaneous electrical nerve stimulation for knee osteoarthritis  [R]
Therapeutic ultrasound
  1. Therapeutic ultrasound for osteoarthritis of the knee  [R]
Thermotherapy
  1. Thermotherapy for treatment of osteoarthritis  [R]  [S]

Surgical

  1. Cemented versus cementless total hip arthroplasty for osteoarthritis and other non-traumatic diseases  [P]

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Osteoarthritis - Rehabilitation  Aquatic exercise
  1. Aquatic exercise for the treatment of knee and hip osteoarthritis  [R]
Exercise therapy
  1. Home versus center based physical activity programs for older adults  [R]  [S]
  2. Intensity of exercise for the treatment of osteoarthritis  [R]  [S]
  3. Exercise for osteoarthritis of the hip or knee  [R]  [S]
  4. Post-acute physiotherapy for primary total knee arthroplasty [P]
Patient education
  1. Patient education for osteoarthritis  [P]
  2. Pre-operative education for hip or knee replacement  [R]  [S]
Continuous passive motion
  1. Continuous passive motion following total knee arthroplasty  [R]  [S]
Modalities
  1. Electromagnetic fields for the treatment of osteoarthritis  [R]
  2. Isokinetic exercise for improving knee flexor and extensor muscles  [P]
  3. Traction for hip osteoarthritis  [P]
Splints/othoses
  1. Braces and orthoses for treating osteoarthritis of the knee  [R]  [S]

Multidisciplinary Rehabilitation

  1. Multidisciplinary rehabilitation programmes following joint replacement at the hip and knee in chronic arthropathy [R] 

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Osteoporosis - Prevention Diet
  1. Phytoestrogens in the treatment of postmenopausal osteoporosis  [P]
Exercise
  1. Exercise for preventing and treating osteoporosis in postmenopausal women   [R]
  2. Exercise for preventing low bone mass in young males and females  [P]
  3. Physical activity for preventing and treating osteoporosis in men  [P]

Other

  1. Gonadotrophin-releasing hormone analogues for endometriosis: bone mineral density  [R]
  2. Alendronate for the primary and secondary prevention of osteoporotic fractures in postmenopausal women  [R]
  3. Etidronate for the primary and secondary prevention of osteoporotic fractures in postmenopausal women  [R]
  4. Risedronate for the primary and secondary prevention of osteoporotic fractures in postmenopausal women  [R]

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Osteoporosis - Pharmacological Treatment Bisphosphonates (bisphosphonates/alendronate/clodronate/etidronate/ibandronate/risendronate)
  1. Bisphosphonates for steroid induced osteoporosis  [R]
  2. Alendronate for osteoporosis in postmenopausal women  [P]
  3. Bisphosphonate therapy for osteoporosis in children and adolescents without osteogenesis imperfecta  [P]
  4. Bisphosphonate therapy for children and adolescents with secondary osteoporosis  [R]
Pamidronate (Zolendronate)
  1. No reviews on this topic
Calcium and Calcium/vitamin D combinations
  1. Calcium and vitamin D for corticosteroid-induced osteoporosis  [R]
  2. Calcium supplementation for improving bone mineral density in children  [R]
Calcitonin
  1. Calcitonin for preventing and treating corticosteroid-induced osteoporosis  [R]
  2. Calcitonin for treating osteoporosis in postmenopausal women  [P]
Fluoride
  1. Fluoride for treating postmenopausal osteoporosis  [R]
Growth Hormone
  1. No reviews on this topic

Herbal

  1. Herbal medicines for treating osteoporosis  [P]
Hormone Replacement Therapy
  1. Hormone replacement therapy for osteoporosis in postmenopausal women  [P]
  2. Tibolone for the prevention and treatment of postmenopausal osteoporosis  [P]
Selective estrogen receptor modulators (SERMS) - 
(Nandrolone decanoate/Raloxifene/Tibolone)
  1. Raloxifene for the prevention and treatment of osteoporosis in post-menopausal women  [P]
Ipriflavone
  1. No reviews on this topic
Parathyroid hormone
  1. Human parathyroid hormone for the treatment of osteoporosis in post-menopausal women   [P]
Vitamin D
  1. Vitamin D with or without calcium for treating osteoporosis in postmenopausal women  [P]
Calcitrol/Cholecalciferol/Alternative therapies
  1. No reviews on these topics
Statins
  1. Statins for osteoporosis in postmenopausal women  [P]

Strontium Ralenate

  1. Strontium ranelate for preventing and treating postmenopausal osteoporosis  [R]  [S]

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Osteoporosis - Rehabilitation Exercise
  1. Exercise for preventing and treating osteoporosis in postmenopausal women  [R]
Patient education
  1. Pre-operative education for hip or knee replacement  [R]

Other

  1. Arthroplasties (with and without bone cement) for proximal femoral fractures in adults  [R]
  2. Gamma and other cephalocondylic intramedullary nails versus extramedullary implants for extracapsular hip fractures  [R]  [s]
  3. Perioperative fluid volume optimization following proximal femoral fracture  [R]  [s]
  4. Hip protectors for preventing hip fractures in the elderly  [R] [s]
  5. Internal fixation versus arthroplasty for intracapsular proximal femoral fractures in adults  [R] [s]
  6. Mobilisation strategies after hip fracture surgery in adults  [R]  [s]
  7. Pre-operative traction for fractures of the proximal femur in adults  [R] [s]
  8. Closed reduction methods for treating distal radial fractures in adults  [R]  [s]
  9. Conservative interventions for treating distal radial fractures in adults  [R]  [S]
  10. Surgical interventions for treating distal radial fractures in adults  [R]  [s]
  11. Bone grafts and bone substitutes for treating distal radial fractures in adults  [P]
  12. Different methods of external fixation for treating distal radial fractures in adults  [R]
  13. Internal fixation and comparisons of different fixation methods for treating distal radial fractures in adults  [P]
  14. Internal versus external fixation for treating distal tibial pilon fractures in adults  [P]
  15. Bone grafts and bone substitutes for treating distal radial fractures in adults  [R]

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Rheumatoid Arthritis - Prevention Diet
  1. No reviews on this topic

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Rheumatoid Arthritis - Pharmacological Treatment  
Disease controlling antirheumatic therapy (DCARTs only)
  1. No reviews on this topics

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Disease modifying antirheumatic drugs (DMARDs) and slow acting antirheumatic drugs, second line agents (SAARDs) Methotrexate
  1. Folic acid and folinic acid for reducing side effects in patients receiving methotrexate for rheumatoid arthritis  [R]
  2. Methotrexate for treating rheumatoid arthritis  [R]
Gold, auranofin, myochrisine, solgonal
  1. Injectable gold for rheumatoid arthritis  [R]
  2. Auranofin versus placebo in rheumatoid arthritis  [R]
Hydroxychloroquine/Choroquine
  1. Antimalarials for treating rheumatoid arthritis  [R]
Azathioprine
  1. Azathioprine for treating rheumatoid arthritis  [R]
Cyclosphosphamide
  1. Cyclophosphamide for treating rheumatoid arthritis  [R]
Cyclosporine
  1. Cyclosporine for treating rheumatoid arthritis  [R]
Leflunomide
  1. Leflunomide for treating rheumatoid arthritis  [R] [s]
Sulfasalazine
  1. Sulfasalazine for treating rheumatoid arthritis  [R]
Eythropoietin
  1. Erythropoietin for anaemia in rheumatoid arthritis  [P]
Anakinra
  1. Anakinra for rheumatoid arthritis  [P]

Penicillamine

  1. Penicillamine for treating rheumatoid arthritis  [R]

Nitrogen Mustard/Mycophenolic acid/Antimicrobial

  1. No reviews under these topics

Biologics

  1. Adalimumab for treating rheumatoid arthritis  [R]
  2. Anakinra for rheumatoid arthritis  [P]

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Symptom modifying antirheumatic drugs (SMARDs)  Non-steroidal anti-inflammatory drugs (NSAIDs)
  1. Paracetamol versus nonsteroidal anti-inflammatory drugs for rheumatoid arthritis  [R]  [s]
Selective Cox 2 inhibitors (NSAIDs)
  1. Rofecoxib for rheumatoid arthritis  [R]
  2. Celecoxib for rheumatoid arthritis  [R]  [S]
Analgesics
  1. Opioid therapy for treating rheumatoid arthritis pain  [P]
Corticosteroids
  1. Moderate-term, low-dose corticosteroids for rheumatoid arthritis  [R]
  2. Short-term low-dose corticosteroids versus placebo and nonsteroidal antiinflammatory drugs in rheumatoid arthritis  [R] [s]
Biologics (AntiCD4, Anti TNF)
  1. Infliximab for the treatment of rheumatoid arthritis  [R]
  2. Etanercept for the treatment of rheumatoid arthritis  [R] [s]
Fish Oil/Radiation Synovectomy (Yttrium90)/Bone Marrow Transplant (stem cell transplant)
  1. No reviews on these topics

Steroids

  1. Glucocorticoids for slowing radiological progression in rheumatoid arthritis  [P]

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Rheumatoid Arthritis - Non-Pharmacological Treatment Surgery
  1. Mobile bearing and fixed bearing prostheses for total knee arthroplasty for post-operative functional status in patients with osteoarthritis and rheumatoid arthritis  [R]  [S]
  2. Surgical interventions for the rheumatoid shoulder  [P]
Alternative therapies
  1. Herbal therapy for treating rheumatoid arthritis  [R]
  2. Tai chi for treating rheumatoid arthritis  [R] [s]
  3. Dietary interventions for rheumatoid arthritis  [P]
  4. Dynamic exercise for treating rheumatoid arthritis  [P]

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Rheumatoid Arthritis - Rehabilitation Occupational therapy
  1. Splints and Orthosis for treating rheumatoid arthritis  [R] [s]
  2. Occupational therapy for rheumatoid arthritis  [R] [s]
Physical therapy - Exercise
  1. Aquatic therapy exercise for treating rheumatoid arthritis  [P]
  2. Exercise therapy for the rheumatoid hand  [P]
  3. Cyclophosphamide for treating rheumatoid arthritis   [R]
  4. Dynamic exercise therapy for treating rheumatoid arthritis  [R]
  5. Post-operative therapy for metacarpophalangeal arthroplasty  [R]
  6. Comprehensive physiotherapy for rheumatoid arthritis  [P]
  7. Physiotherapy interventions for ankylosing spondylitis  [R]
Physical therapy - Thermotherapy
  1. Thermotherapy for treating rheumatoid arthritis   [R]
Physical therapy - Balneotherapy
  1. Balneotherapy for rheumatoid arthritis  [R] [s]
Physical therapy - Electrotherapy
  1. Low level laser therapy (Classes I, II and III) for treating rheumatoid arthritis  [R]
  2. Acupuncture  and electroacupuncture for the treatment of rheumatoid arthritis  [R]  [S]
  3. Therapeutic ultrasound for the treatment of rheumatoid arthritis  [R]
  4. Electrical stimulation for the treatment of rheumatoid arthritis  [R]
  5. Transcutaneous electrical nerve stimulation (TENS) for the treatment of rheumatoid arthritis in the hand   [R]  [S]
Education
  1. Patient education for adults with rheumatoid arthritis  [R] [s]

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Last updated 12 Jun 2008

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