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Arthritis and Musculoskeletal reviews by topic

Issue 7, 2010 of The Cochrane Library included 1 review and 1 protocol on arthritis and musculoskeletal disease.   A full list of topics and reviews can be viewed below. 

Click on the title to view the full review or protocol

Log on to The Cochrane Library to read protocols and full reviews. (click here for search tip)

[R] Cochrane review

[P] Protocol for Cochrane review

[S] Summary of Cochrane review available

Quick links to topics:

Topic Reviews and Protocols 
Click on title to view review or protocol
Osteoarthritis - Prevention
  1. Interventions for improving the appropriate use of imaging in people with musculoskeletal conditions  [R]

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Osteoarthritis - Pharmacological Treatment Analgesia
  1. Chloroquines for the treatment of osteoarthritis  [P]
  2. Nerve blocks (subcostal, lateral cutaneous, femoral, triple, psoas) for hip fractures  [R]
  3. Oral or transdermal opioids for osteoarthritis of the knee or hip  [R]
  4. Tramadol for osteoarthritis  [R]  [S]

Chondroitin

  1. Chondroitin for osteoarthritis  [P]
Glucosamine
  1. Glucosamine therapy for treating osteoarthritis  [R]
Intra-articular injections
  1. Intraarticular corticosteroids for osteoarthritis of the knee  [R]  [S]
Non-steroidal anti-inflammatory drugs (NSAID)
  1. Acetaminophen for osteoarthritis  [R]  [S]
  2. Doxycycline for osteoarthritis of the knee or hip  [R]
Selective Cox 2 inhibitors
  1. Rofecoxib for osteoarthritis  [R]
Viscosupplemenation
  1. Viscosupplementation for osteoarthritis of the knee  [R]
Hormone replacement therapy
  1. Hormone replacement therapy for osteoarthritis in peri-menopausal and post-menopausal women  [P]

Biologics

  1. Diacerein for osteoarthritis  [R]  [S]

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Osteoarthritis - Non-Pharmacological Treatment Alternative therapies (eg. acupuncture)
  1. Acupuncture for osteoarthritis  [R]
  2. Exercise for osteoarthritis of the knee  [R]
  3. Herbal therapy for treating osteoarthritis  [R]
  4. Homeopathy for osteoarthritis  [P]
  5. Interventions for the management of temporomandibular joint osteoarthritis  [P]
  6. Interventions for treating osteoarthritis of the big toe joint  [P]
  7. Psychological therapies for the management of chronic pain (excluding headache) in adults  [R]
  8. S-Adenosylmethionine for osteoarthritis of the knee or hip  [R]
  9. Taping for knee osteoarthritis  [P]
Balneotherapy
  1. Balneotherapy for osteoarthritis  [R]
  2. Balneotherapy for rheumatoid arthritis  [R]
Laser therapy
  1. Low level laser therapy (Classes I, II and III) for treating osteoarthritis  [R]  [S]
Surgery
  1. Arthroscopic debridement for knee osteoarthritis  [R]
  2. Cemented versus cementless surgical approach for total hip arthroplasty revision  [P]
  3. Computer assisted knee arthroplasty for osteoarthritis and other non-traumatic diseases  [P]
  4. Effects of different bearing surface materials on aseptic loosening of total hip arthroplasty in patients with osteoarthritis and other non-traumatic diseases of the hip  [P]
  5. Joint lavage for osteoarthritis of the knee  [R]
  6. Metal versus non-metal backing of the tibial component for total knee replacement for osteoarthritis and/or rheumatoid arthritis  [P]
  7. Minimally invasive surgical approaches for total hip athroplasty in adults with osteoarthritis  [P]
  8. Mobile bearing and fixed bearing prostheses for total knee arthroplasty for post-operative functional status in patients with osteoarthritis and rheumatoid arthritis  [R]  [S]
  9. Non-steroidal anti-inflammatory drugs for preventing heterotophic bone formation after hip arthroplasty  [R]  [S]
  10. Operative and non‑operative treatment options for dislocation of the hip following total hip arthroplasty  [R]
  11. Osteotomy, compression and other modifications of surgical techniques for internal fixation of extracapsular hip fractures  [R]
  12. Osteotomy for treating knee osteoarthritis  [R]  [S]
  13. Patella resurfacing in total knee arthroplasty  [P]
  14. Posterior versus lateral surgical approach for total hip arthroplasty in adults with osteoarthritis  [R]  [S]
  15. Processed versus fresh frozen bone for impaction bone grafting in revision hip arthroplasty  [P]
  16. Retention versus sacrifice of the posterior cruciate ligament in total knee replacement for treatment of osteoarthritis and rheumatoid arthritis  [R]
  17. Surgery for shoulder osteoarthritis  [P]
  18. Surgery for thumb (trapeziometacarpal joint) osteoarthritis  [R]
  19. Surgical approaches in total knee arthroplasty  [P]
TENS
  1. Transcutaneous electrical nerve stimulation for acute pain  [R]
  2. Transcutaneous electrical nerve stimulation (TENS) for chronic pain  [R]
  3. Transcutaneous electrostimulation for osteoarthritis of the knee  [R]
Therapeutic ultrasound
  1. Therapeutic ultrasound for osteoarthritis of the knee or hip  [R]
Thermotherapy
  1. Thermotherapy for treatment of osteoarthritis  [R]  [S]

Surgical

  1. Cemented versus cementless total hip arthroplasty for osteoarthritis and other non-traumatic diseases  [P]

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Osteoarthritis - Rehabilitation  Aquatic exercise
  1. Aquatic exercise for the treatment of knee and hip osteoarthritis  [R]
Exercise therapy
  1. Exercise for osteoarthritis of the hip  [R]
  2. Home versus center based physical activity programs for older adults  [R]  [S]
  3. Intensity of exercise for the treatment of osteoarthritis  [R]  [S]
  4. Post-acute physiotherapy for primary total knee arthroplasty [P]
Patient education
  1. Pre-operative education for hip or knee replacement  [R]  [S]
Continuous passive motion
  1. Continuous passive motion following total knee arthroplasty  [R]  [S]
Modalities
  1. Electromagnetic fields for the treatment of osteoarthritis  [R]
  2. Isokinetic exercise for improving knee flexor and extensor muscles  [P]
  3. Traction for hip osteoarthritis  [P]
Splints/othoses
  1. Braces and orthoses for treating osteoarthritis of the knee  [R]  [S]

Multidisciplinary Rehabilitation

  1. Multidisciplinary rehabilitation programmes following joint replacement at the hip and knee in chronic arthropathy [R] 
  2. Rehabilitation interventions for improving physical and psychosocial functioning after hip fracture in older people  [R]

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Osteoporosis - Prevention Diet
  1. Phytoestrogens in the treatment of postmenopausal osteoporosis  [P]
  2. Vitamin D and vitamin D analogues for preventing fractures associated with involutional and post-menopausal osteoporosis  [R]
  3. Vitamin K for the prevention and treatment of osteoporosis in post-menopausal women  [P]
Exercise
  1. Exercise for preventing and treating osteoporosis in postmenopausal women   [R]
  2. Exercise for preventing low bone mass in young males and females  [P]
  3. Physical activity for preventing and treating osteoporosis in men  [P]

Other

  1. Alendronate for the primary and secondary prevention of osteoporotic fractures in postmenopausal women  [R]
  2. Etidronate for the primary and secondary prevention of osteoporotic fractures in postmenopausal women  [R]
  3. Gonadotrophin-releasing hormone analogues for endometriosis: bone mineral density  [R]
  4. Risedronate for the primary and secondary prevention of osteoporotic fractures in postmenopausal women  [R]

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Osteoporosis - Pharmacological Treatment Bisphosphonates (bisphosphonates/alendronate/clodronate/etidronate/ibandronate/risendronate)
  1. Alendronate for osteoporosis in postmenopausal women  [P]
  2. Bisphosphonates for osteoporosis in people with cystic fibrosis  [R]
  3. Bisphosphonates for steroid induced osteoporosis  [R]
  4. Bisphosphonate therapy for children and adolescents with secondary osteoporosis  [R]
  5. Bisphosphonate therapy for osteoporosis in children and adolescents without osteogenesis imperfecta  [P]
  6. Intravenous zoledronate for postmenopausal osteoporosis  [P]
Pamidronate (Zolendronate)
  1. No reviews on this topic
Calcium and Calcium/vitamin D combinations
  1. Calcium and vitamin D for corticosteroid-induced osteoporosis  [R]
  2. Calcium supplementation for improving bone mineral density in children  [R]
Calcitonin
  1. Calcitonin for preventing and treating corticosteroid-induced osteoporosis  [R]
Fluoride
  1. Fluoride for treating postmenopausal osteoporosis  [R]
Growth Hormone
  1. No reviews on this topic

Herbal

  1. Herbal medicines for treating osteoporosis  [P]
  2. Nutritional supplementation for hip fracture aftercare in older people  [R]
Hormone Replacement Therapy

Selective estrogen receptor modulators (SERMS) - 
(Nandrolone decanoate/Raloxifene/Tibolone)

Ipriflavone
  1. No reviews on this topic
Parathyroid hormone
  1. Human parathyroid hormone for the treatment of osteoporosis in post-menopausal women   [P]
Vitamins
  1. Vitamin D with or without calcium for treating osteoporosis in postmenopausal women  [P]
  2. Vitamin K for the prevention and treatment of osteoporosis in post-menopausal women  [P]
Calcitrol/Cholecalciferol/Alternative therapies
  1. No reviews on these topics
Statins
  1. Statins for osteoporosis in postmenopausal women  [P]

Strontium Ralenate

  1. Strontium ranelate for preventing and treating postmenopausal osteoporosis  [R]  [S]

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Osteoporosis - Rehabilitation Exercise
  1. Exercise for preventing and treating osteoporosis in postmenopausal women  [R]
Patient education
  1. Pre-operative education for hip or knee replacement  [R]

Other

  1. Arthroplasties (with and without bone cement) for proximal femoral fractures in adults  [R]
  2. Bone grafts and bone substitutes for treating distal radial fractures in adults  [R]
  3. Closed reduction methods for treating distal radial fractures in adults  [R]  [s]
  4. Conservative interventions for treating distal radial fractures in adults  [R]  [S]
  5. Conservative versus operative treatment for hip fractures in adults  [R]
  6. Different methods of external fixation for treating distal radial fractures in adults  [R]
  7. Gamma and other cephalocondylic intramedullary nails versus extramedullary implants for extracapsular hip fractures in adults  [R]  [s]
  8. Hip protectors for preventing hip fractures in the elderly  [R] [s]
  9. Internal fixation and comparisons of different fixation methods for treating distal radial fractures in adults  [P]
  10. Internal fixation versus arthroplasty for intracapsular proximal femoral fractures in adults  [R] [s]
  11. Internal versus external fixation for treating distal tibial pilon fractures in adults  [P]
  12. Mobilisation strategies after hip fracture surgery in adults  [R]  [s]
  13. Multidisciplinary rehabilitation for older people with hip fractures  [R]
  14. Perioperative fluid volume optimization following proximal femoral fracture  [R]  [s]
  15. Pre-operative traction for fractures of the proximal femur in adults  [R] [s]
  16. Surgical interventions for treating distal radial fractures in adults  [R]  [s]

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Rheumatoid Arthritis - Prevention Diet
  1. No reviews on this topic

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Rheumatoid Arthritis - Pharmacological Treatment  
Disease controlling antirheumatic therapy (DCARTs only)
  1. No reviews on this topics

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Disease modifying antirheumatic drugs (DMARDs) and slow acting antirheumatic drugs, second line agents (SAARDs) General
  1. Certolizumab pegol (CDP870) for rheumatoid arthritis in adults  [P]
  2. Disease modifying anti-rheumatic drugs in people with cystic fibrosis-related arthritis  [R]

Methotrexate

  1. Folic acid and folinic acid for reducing side effects in patients receiving methotrexate for rheumatoid arthritis  [R]
  2. Methotrexate for treating rheumatoid arthritis  [R]
  3. Methotrexate monotherapy versus methotrexate combination therapy with non-biologic disease modifying anti-rheumatic drugs for rheumatoid arthritis  [R]
Gold, auranofin, myochrisine, solgonal
  1. Auranofin versus placebo in rheumatoid arthritis  [R]
  2. Injectable gold for rheumatoid arthritis  [R]
Hydroxychloroquine/Choroquine
  1. Antimalarials for treating rheumatoid arthritis  [R]
Azathioprine
  1. Azathioprine for treating rheumatoid arthritis  [R]
Cyclosphosphamide
  1. Cyclophosphamide for treating rheumatoid arthritis  [R]
Cyclosporine
  1. Cyclosporine for treating rheumatoid arthritis  [R]
Leflunomide
  1. Leflunomide for the treatment of rheumatoid arthritis  [R]
Sulfasalazine
  1. Sulfasalazine for treating rheumatoid arthritis  [R]
Eythropoietin
  1. Erythropoietin for anaemia in rheumatoid arthritis  [P]
Anakinra
  1. Anakinra for rheumatoid arthritis  [R]

Penicillamine

  1. Penicillamine for treating rheumatoid arthritis  [R]

Nitrogen Mustard/Mycophenolic acid/Antimicrobial

  1. No reviews under these topics

Biologics

  1. Abatacept for rheumatoid arthritis  [R]
  2. Adalimumab for treating rheumatoid arthritis  [R]
  3. Anakinra for rheumatoid arthritis  [P]
  4. Biologic interventions for fatigue in rheumatoid arthritis  [P]
  5. Biologics for rheumatoid arthritis: an overview of Cochrane reviews  [R]
  6. Golimumab for rheumatoid arthritis  [R]
  7. Rituximab for rheumatoid arthritis  [P]
  8. Tocilizumab for rheumatoid arthritis  [R]

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Symptom modifying antirheumatic drugs (SMARDs)  Non-steroidal anti-inflammatory drugs (NSAIDs)
  1. Paracetamol versus nonsteroidal anti-inflammatory drugs for rheumatoid arthritis  [R]  [s]
Selective Cox 2 inhibitors (NSAIDs)
  1. Celecoxib for rheumatoid arthritis  [R]  [S]
  2. Rofecoxib for rheumatoid arthritis  [R]
Analgesics
  1. Anti-inflammatory drugs and analgesics for managing symptoms in people with cystic fibrosis-related arthritis  [R]
  2. Opioid therapy for treating rheumatoid arthritis pain  [P]
  3. Topical rubefacients for acute and chronic pain in adults  [R]
Corticosteroids
  1. Anti-inflammatory drugs and analgesics for managing symptoms in people with cystic fibrosis-related arthritis  [R]
  2. Moderate-term, low-dose corticosteroids for rheumatoid arthritis  [R]
  3. Short-term low-dose corticosteroids versus placebo and nonsteroidal antiinflammatory drugs in rheumatoid arthritis  [R] [s]
Biologics (AntiCD4, Anti TNF)
  1. Etanercept for the treatment of rheumatoid arthritis  [R] [s]
  2. Infliximab for the treatment of rheumatoid arthritis  [R]
Fish Oil/Radiation Synovectomy (Yttrium90)/Bone Marrow Transplant (stem cell transplant)
  1. No reviews on these topics

Steroids

  1. Effects of glucocorticoids on radiological progression in rheumatoid arthritis  [R]

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Rheumatoid Arthritis - Non-Pharmacological Treatment Surgery
  1. Mobile bearing and fixed bearing prostheses for total knee arthroplasty for post-operative functional status in patients with osteoarthritis and rheumatoid arthritis  [R]  [S]
  2. Surgical interventions for the rheumatoid shoulder  [R]
Other therapies
  1. Assistive technology for rheumatoid arthritis  [R]
  2. Balance training (proprioceptive training) for patients with rheumatoid arthritis  [R]
  3. Dietary interventions for rheumatoid arthritis  [R]
  4. Dynamic exercise for treating rheumatoid arthritis  [P]
  5. Dynamic exercise programs (aerobic capacity and/or muscle strength training) in patients with rheumatoid arthritis  [R]
  6. Herbal therapy for treating rheumatoid arthritis  [R]
  7. Home-based exercise therapy for rheumatoid arthritis  [P]
  8. Non-pharmacological interventions for fatigue in rheumatoid arthritis  [P]
  9. Tai chi for treating rheumatoid arthritis  [R] [s]
  10. Vitamin D for the treatment of chronic painful conditions in adults  [R]

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Rheumatoid Arthritis - Rehabilitation Occupational therapy
  1. Occupational therapy for rheumatoid arthritis  [R] [s]
  2. Splints and Orthosis for treating rheumatoid arthritis  [R] [s]
Physical therapy - Exercise
  1. Aquatic therapy exercise for treating rheumatoid arthritis  [P]
  2. Comprehensive physiotherapy for rheumatoid arthritis  [P]
  3. Cyclophosphamide for treating rheumatoid arthritis   [R]
  4. Dynamic exercise therapy for treating rheumatoid arthritis  [R]
  5. Exercise therapy for the rheumatoid hand  [P]
  6. Physiotherapy interventions for ankylosing spondylitis  [R]
  7. Post-operative therapy for metacarpophalangeal arthroplasty  [R]
Physical therapy - Thermotherapy
  1. Thermotherapy for treating rheumatoid arthritis   [R]
Physical therapy - Balneotherapy
  1. Balneotherapy for rheumatoid arthritis  [R] [s]
Physical therapy - Electrotherapy
  1. Acupuncture  and electroacupuncture for the treatment of rheumatoid arthritis  [R]  [S]
  2. Electrical stimulation for the treatment of rheumatoid arthritis  [R]
  3. Low level laser therapy (Classes I, II and III) for treating rheumatoid arthritis  [R]
  4. Therapeutic ultrasound for the treatment of rheumatoid arthritis  [R]
  5. Transcutaneous electrical nerve stimulation (TENS) for the treatment of rheumatoid arthritis in the hand   [R]  [S]
Education
  1. Patient education for adults with rheumatoid arthritis  [R] [s]

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Last updated 19 Jul 2010

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